- Anatomy of The Spine
- Back Pain in Children
- Caring for your Spine
- Emerging Spinecare Trends
- Evaluation of Spinal Disorders
- Exercise and The Spine
- Intervention - Spinal Disorders
- Intervertebral Disc
- Non Surgical Options
- Nutrition and Spinecare
- Options for Spine Treatments
- Pregnancy and Back Pain
- Prevalence of Spine Disorders
- Sleep and the Spine
- Spinecare Introduction
- Spinehealth and Disease
- Surgical Interventions
- Treatment with Medications
- Understanding Back Pain
Spinecare Topics
Spinehealth and Disease
The Healing Spine
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The Healing Spine
Remodeling and Recovery in Spinal Tissues:
The bone, cartilage, tendons, ligaments, and outer annular fibers of the intervertebral disc remodel based upon the mechanical stress placed upon them. This process is also referred to functional adaptation, which states that an ordinary tissue will adapt to self chemically and structurally to the function it has to perform. According to Wolf’s Law, bones are subjected to stress demands in wieghtbearing posture, they will model or alter their shape accordingly. Wolf’s Law has a less well-known corollary for soft tissue called Davis’ Law, that states: Soft tissue will remodel according to imposed demands. Connective tissue is a supporting system that cements and binds together specialized tissue fibers within the human body and the spine. The connective tissues of the spine serve to help anchor parts as well as performing other functions such as providing support, defense and the capacity for tissue repair. Connective tissue responds by adapting to the stresses placed upon them. This process is referred to as morphogenesis and remodeling.
There are specialized cells within the connective tissues of the spine referred to as fibroblasts. The fibroblasts are essentially the stars of the connective tissue show. Fibroblasts manufacture and maintain the extracellular material. Fibroblasts also move throughout the ECM wherever they are needed, such as scar formation. Fibroblasts rapidly enter sites of tissue injury. They produce a variety of chemicals that influence and coordinate the inflammatory and reparative process. The chemical plays an important role in activation of inflammation and connective tissue cells during the tissue repair process.
The connective tissues of the spine help to hold it together. The various types of connective tissues include fibrous and elastic connective tissues, the adipose (fatty) tissues, cartilage and bone. The connective tissues have a limited blood supply in fact many are avascular (without a blood supply).
The most common connective tissue cells are fibroblasts, adipocytes (fat cells), mast cells, macrophages and lymphocytes. Connective tissue matrix cells is composed of: ground substance and fibers. The ground substance of connective tissue is comprised of water stabilized by glycosaminoglycans, proteoglycans, and glycoproteins. The principal fiber type of connective tissue is collagen the most abundant protein in the body that confers tensile strength with flexibility. Elastic connective tissue fibers provide resiliency.
Note that connective tissues form a significant and vitally important component of nearly every organ including the spine. †When damage occurs, perfect restoration of function requires the replacement of lost cells by like cells thus the term regeneration. Also required is preservation of the orderly arrangement (architecture) of the tissues. When both conditions are present, the result is perfect restoration.
The bone, cartilage, tendons, ligaments, and outer annular fibers of the intervertebral disc remodel based upon the mechanical stress placed upon them. This process is also referred to functional adaptation, which states that an ordinary tissue will adapt to self chemically and structurally to the function it has to perform. According to Wolf’s Law, bones are subjected to stress demands in wieghtbearing posture, they will model or alter their shape accordingly. Wolf’s Law has a less well-known corollary for soft tissue called Davis’ Law, that states: Soft tissue will remodel according to imposed demands. Connective tissue is a supporting system that cements and binds together specialized tissue fibers within the human body and the spine. The connective tissues of the spine serve to help anchor parts as well as performing other functions such as providing support, defense and the capacity for tissue repair. Connective tissue responds by adapting to the stresses placed upon them. This process is referred to as morphogenesis and remodeling.
There are specialized cells within the connective tissues of the spine referred to as fibroblasts. The fibroblasts are essentially the stars of the connective tissue show. Fibroblasts manufacture and maintain the extracellular material. Fibroblasts also move throughout the ECM wherever they are needed, such as scar formation. Fibroblasts rapidly enter sites of tissue injury. They produce a variety of chemicals that influence and coordinate the inflammatory and reparative process. The chemical plays an important role in activation of inflammation and connective tissue cells during the tissue repair process.
The connective tissues of the spine help to hold it together. The various types of connective tissues include fibrous and elastic connective tissues, the adipose (fatty) tissues, cartilage and bone. The connective tissues have a limited blood supply in fact many are avascular (without a blood supply).
The most common connective tissue cells are fibroblasts, adipocytes (fat cells), mast cells, macrophages and lymphocytes. Connective tissue matrix cells is composed of: ground substance and fibers. The ground substance of connective tissue is comprised of water stabilized by glycosaminoglycans, proteoglycans, and glycoproteins. The principal fiber type of connective tissue is collagen the most abundant protein in the body that confers tensile strength with flexibility. Elastic connective tissue fibers provide resiliency.
Note that connective tissues form a significant and vitally important component of nearly every organ including the spine. †When damage occurs, perfect restoration of function requires the replacement of lost cells by like cells thus the term regeneration. Also required is preservation of the orderly arrangement (architecture) of the tissues. When both conditions are present, the result is perfect restoration.
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